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Secondary thiols can be prepared from the ketone via the corresponding dithioketals

The standard escalation protocol Your healthcare provider will typically increase your dose by 2.5 mg every 4 weeks, following this progression: Week 14: 2.5 mg Week 58: 5 mg Week 912: 7.5 mg Week 1316: 10 mg Week 1720: 12.5 mg Week 21+: 15 mg (maximum dose) Four weeks is the minimum time at each dose, but it is not a fixed deadline

Srikumar TS, Johansson GK, Ockerman PA, Gustafsson JA, Akesson B